SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02419

Signal sequence   MVPCTLLLLLAAALAPTQTRA

Length  21

Organism  Mus musculus (Mouse)

UniProt ID  P01901,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02419.cif

Structure  SPKB02419.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2167.69654

Aliphatic index  149.047619

Isoelectric point  8.549912035

Charge (pH=7)   0.936006272

Topological polar surface area  793.42

Aromaticity  0

Average rotatable bonds  3.142857143

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  29

X logP energy  -5.50713

Hydropathy 



Literature Information


Title  Amino acid sequence of the carboxyl-terminal hydrophilic region of the H-2Kb MHC alloantigen. Completion of the entire primary structure of the H-2Kb molecule.

DOI  10.1021/bi00524a003,

Publication Year  1981

PubMed ID  7306483,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.