SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02411

Signal sequence   MNPVISITLLLSVLQMSRG

Length  19

Organism  Rattus norvegicus (Rat)

UniProt ID  P01830,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02411.cif

Structure  SPKB02411.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2072.55234

Aliphatic index  153.6842105

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  807.33

Aromaticity  0

Average rotatable bonds  3.631578947

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  29

X logP energy  -6.88103

Hydropathy 



Literature Information


Title  Rat brain Thy-1 glycoprotein. The amino acid sequence, disulphide bonds and an unusual hydrophobic region.

DOI  10.1042/bj1950015,

Publication Year  1981

PubMed ID  6118137,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.