General Information
SPKB ID SPKB02408
Signal sequence MELGLSWVFLVAILEGVQC
Length 19
Organism Homo sapiens (Human)
UniProt ID P01780,
Motif 1..19
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02408.cif
Physicochemical Information
Molecular weight 2107.55374
Aliphatic index 153.6842105
Isoelectric point 3.613682238
Charge (pH=7) -2.060440171
Topological polar surface area 740.83
Aromaticity 0.105263158
Average rotatable bonds 3.578947368
Number of hydrogen bond donors 26
Number of hydrogen bond acceptors 26
X logP energy -1.7571
Hydropathy 
Literature Information
Title Variable region sequences of five human immunoglobulin heavy chains of the VH3 subgroup: definitive identification of four heavy chain hypervariable regions.
Publication Year 1974
PubMed ID 4522793,
Patent ID NA,
