General Information
SPKB ID SPKB02407
Signal sequence MEFGLSWVFLVALLRGVQC
Length 19
Organism Homo sapiens (Human)
UniProt ID P01768,
Motif 1..19
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 6PWU,
Predicted Structure ID SPKB02407.cif
Physicochemical Information
Molecular weight 2168.64294
Aliphatic index 133.1578947
Isoelectric point 6.232433001
Charge (pH=7) -0.062218605
Topological polar surface area 765.43
Aromaticity 0.157894737
Average rotatable bonds 3.631578947
Number of hydrogen bond donors 28
Number of hydrogen bond acceptors 26
X logP energy -2.16203
Hydropathy 
Literature Information
Title Primary structure of a human IgA1 immunoglobulin. IV. Streptococcal IgA1 protease, digestion, Fab and Fc fragments, and the complete amino acid sequence of the alpha 1 heavy chain.
DOI NA,
Publication Year 1979
PubMed ID 107164,
Patent ID NA,
