SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02406

Signal sequence   MEFGLSWLFLVAILKGVQC

Length  19

Organism  Homo sapiens (Human)

UniProt ID  P01764,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  5D6D,

Predicted Structure ID  SPKB02406.cif

Structure  SPKB02406.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2154.65634

Aliphatic index  138.4210526

Isoelectric point  6.231833229

Charge (pH=7)   -0.062510328

Topological polar surface area  729.55

Aromaticity  0.157894737

Average rotatable bonds  3.684210526

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  26

X logP energy  -0.9062

Hydropathy 



Literature Information


Title  Immunoglobulin structure and genetics. Identity between variable regions of a mu and a gamma2 chain.

DOI  NA,

Publication Year  1977

PubMed ID  409716,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.