General Information
SPKB ID SPKB02405
Signal sequence MDWTWRFLFVVAAATGVQS
Length 19
Organism Homo sapiens (Human)
UniProt ID P01742,
Motif 1..19
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02405.cif
Physicochemical Information
Molecular weight 2185.52814
Aliphatic index 82.10526316
Isoelectric point 6.338718596
Charge (pH=7) -0.001572528
Topological polar surface area 821.68
Aromaticity 0.210526316
Average rotatable bonds 3.421052632
Number of hydrogen bond donors 30
Number of hydrogen bond acceptors 27
X logP energy -4.72623
Hydropathy
Literature Information
Title The covalent structure of a human gamma G-immunoglobulin. VII. Amino acid sequence of heavy-chain cyanogen bromide fragments H1-H4.
DOI 10.1021/bi00818a008,
Publication Year 1970
PubMed ID 5489771,
Patent ID NA,