General Information
SPKB ID SPKB02404
Signal sequence MNRGVPFRHLLLVLQLALLPAATQG
Length 25
Organism Homo sapiens (Human)
UniProt ID P01730,
Motif 1..25
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 4Q6I,
Predicted Structure ID SPKB02404.cif
Physicochemical Information
Molecular weight 2729.32544
Aliphatic index 144.4
Isoelectric point 12.50011018
Charge (pH=7) 2.088886768
Topological polar surface area 1046.12
Aromaticity 0.04
Average rotatable bonds 3.48
Number of hydrogen bond donors 35
Number of hydrogen bond acceptors 34
X logP energy -6.72156
Hydropathy
Literature Information
Title Signal peptide prediction based on analysis of experimentally verified cleavage sites.
DOI 10.1110/ps.04682504,
Publication Year 2004
PubMed ID 15340161,
Patent ID NA,