SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02403

Signal sequence   MAWAPLLLTLLAHCTGSWA

Length  19

Organism  Homo sapiens (Human)

UniProt ID  P01721,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02403.cif

Structure  SPKB02403.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2055.48334

Aliphatic index  123.6842105

Isoelectric point  7.35902981

Charge (pH=7)   0.026918674

Topological polar surface area  699.28

Aromaticity  0.105263158

Average rotatable bonds  3.105263158

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  26

X logP energy  -2.577

Hydropathy 



Literature Information


Title  Comparative study on the structure of the light chains of human immunoglobulins. II. Assignment of a new subgroup.

DOI  10.1093/oxfordjournals.jbchem.a132670,

Publication Year  1979

PubMed ID  118171,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.