SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02402

Signal sequence   MAWALLLLSLLTQGTGSWA

Length  19

Organism  Homo sapiens (Human)

UniProt ID  P01706,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02402.cif

Structure  SPKB02402.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2032.42814

Aliphatic index  138.9473684

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  742.71

Aromaticity  0.105263158

Average rotatable bonds  3.315789474

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  26

X logP energy  -4.0634

Hydropathy 



Literature Information


Title  Amino acid sequence of the human myeloma lambda chain Win.

DOI  10.1016/0005-2795(78)90598-6,

Publication Year  1978

PubMed ID  102365,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.