General Information
SPKB ID SPKB02400
Signal sequence MAWALLLLTLLTQGTGSWA
Length 19
Organism Homo sapiens (Human)
UniProt ID P01704,
Motif 1..19
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 6PWU,
Predicted Structure ID SPKB02400.cif
Physicochemical Information
Molecular weight 2046.45504
Aliphatic index 138.9473684
Isoelectric point 6.099999998
Charge (pH=7) -0.002015701
Topological polar surface area 742.71
Aromaticity 0.105263158
Average rotatable bonds 3.315789474
Number of hydrogen bond donors 27
Number of hydrogen bond acceptors 26
X logP energy -3.6749
Hydropathy 
Literature Information
Title Amino acid sequence of an amyloidogenic Bence Jones protein in myeloma-associated systemic amyloidosis.
DOI 10.1016/0014-5793(85)80757-2,
Publication Year 1985
PubMed ID 3922791,
Patent ID NA,
