SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02398

Signal sequence   MAGFPLLLTLLTHCAGSWA

Length  19

Organism  Homo sapiens (Human)

UniProt ID  P01700,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  2J6E,

Predicted Structure ID  SPKB02398.cif

Structure  SPKB02398.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2002.41984

Aliphatic index  118.4210526

Isoelectric point  7.35902981

Charge (pH=7)   0.026918674

Topological polar surface area  683.49

Aromaticity  0.105263158

Average rotatable bonds  3.105263158

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  26

X logP energy  -3.4468

Hydropathy 



Literature Information


Title  Amino acid sequence of human lambda chains. II. Chymotryptic peptides and sequence of protein Ha.

DOI  NA,

Publication Year  1970

PubMed ID  5532227,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.