SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02397

Signal sequence   MASFPLLLTLLTHCAGSWA

Length  19

Organism  Homo sapiens (Human)

UniProt ID  P01699,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02397.cif

Structure  SPKB02397.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2032.44614

Aliphatic index  118.4210526

Isoelectric point  7.35902981

Charge (pH=7)   0.026918674

Topological polar surface area  703.72

Aromaticity  0.105263158

Average rotatable bonds  3.157894737

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  27

X logP energy  -4.0859

Hydropathy 



Literature Information


Title  The amino acid sequence of a lambda light chain presenting abnormal physicochemical and antigenic features.

DOI  10.1111/j.1432-1033.1985.tb09027.x,

Publication Year  1985

PubMed ID  2410269,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.