General Information
SPKB ID SPKB02396
Signal sequence METPAQLLFLLLLWLPDTTG
Length 20
Organism Homo sapiens (Human)
UniProt ID P01619,
Motif 1..20
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 7X7O,
Predicted Structure ID SPKB02396.cif
Physicochemical Information
Molecular weight 2272.72764
Aliphatic index 141.5
Isoelectric point 3.550073557
Charge (pH=7) -1.999794094
Topological polar surface area 792.81
Aromaticity 0.1
Average rotatable bonds 3.45
Number of hydrogen bond donors 26
Number of hydrogen bond acceptors 28
X logP energy -1.9369
Hydropathy
Literature Information
Title The basic sequences of immunoglobulin kappa chains: Sequence studies of bence jones proteins Rad, Fr 4 and B6.
DOI 10.1016/0014-5793(69)80048-7,
Publication Year 1969
PubMed ID 11946339,
Patent ID NA,