SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02394

Signal sequence   MDMRVPAQLLGLLLLWLPGAKC

Length  22

Organism  Homo sapiens (Human)

UniProt ID  P01602,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02394.cif

Structure  SPKB02394.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2439.07654

Aliphatic index  146.3636364

Isoelectric point  8.545113874

Charge (pH=7)   0.936157722

Topological polar surface area  840.94

Aromaticity  0.045454545

Average rotatable bonds  3.545454545

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  30

X logP energy  -1.83473

Hydropathy 



Literature Information


Title  The primary structure of the Bence-Jones protein Kue. The amino acid sequence of the variable part of a human L-chain of the kappa-type (author's transl)

DOI  NA,

Publication Year  1979

PubMed ID  112021,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.