General Information
SPKB ID SPKB02392
Signal sequence MDMRVPAQLLGLLLLWLSGARC
Length 22
Organism Homo sapiens (Human)
UniProt ID P01593,
Motif 1..22
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 8JBV,
Predicted Structure ID SPKB02392.cif
Physicochemical Information
Molecular weight 2457.05144
Aliphatic index 146.3636364
Isoelectric point 8.54983383
Charge (pH=7) 0.936449445
Topological polar surface area 905.84
Aromaticity 0.045454545
Average rotatable bonds 3.636363636
Number of hydrogen bond donors 33
Number of hydrogen bond acceptors 31
X logP energy -4.21436
Hydropathy 
Literature Information
Title Structural and idiotypic characterization of the L chains of human IgM autoantibodies with different specificities.
DOI NA,
Publication Year 1989
PubMed ID 2496160,
Patent ID NA,
