General Information
SPKB ID SPKB02391
Signal sequence MKNHLLFWGVLAVFIKAVHVKA
Length 22
Organism Homo sapiens (Human)
UniProt ID P01591,
Motif 1..22
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 6LX3,
Predicted Structure ID SPKB02391.cif
Physicochemical Information
Molecular weight 2522.13884
Aliphatic index 137.2727273
Isoelectric point 11.10310314
Charge (pH=7) 3.17891738
Topological polar surface area 868.72
Aromaticity 0.136363636
Average rotatable bonds 3.727272727
Number of hydrogen bond donors 30
Number of hydrogen bond acceptors 30
X logP energy -0.7649
Hydropathy
Literature Information
Title Human Basal Tear Peptidome Characterization by CID, HCD, and ETD Followed by in Silico and in Vitro Analyses for Antimicrobial Peptide Identification.
DOI 10.1021/acs.jproteome.5b00179,
Publication Year 2015
PubMed ID 25946035,
Patent ID NA,