SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02389

Signal sequence   MKYTSYILAFQLCIVLGSLGCYC

Length  23

Organism  Homo sapiens (Human)

UniProt ID  P01579,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02389.cif

Structure  SPKB02389.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2590.16674

Aliphatic index  118.6956522

Isoelectric point  8.030963098

Charge (pH=7)   0.809213875

Topological polar surface area  894.01

Aromaticity  0.173913043

Average rotatable bonds  3.565217391

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  36

X logP energy  -4.3308

Hydropathy 



Literature Information


Title  Structural characterization of human interferon gamma. Heterogeneity of the carboxyl terminus.

DOI  10.1111/j.1432-1033.1987.tb13494.x,

Publication Year  1987

PubMed ID  3109913,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.