SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02387

Signal sequence   MALPFALMMALVVLSCKSSCSLG

Length  23

Organism  Homo sapiens (Human)

UniProt ID  P01570,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02387.cif

Structure  SPKB02387.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2373.00134

Aliphatic index  123.0434783

Isoelectric point  8.229691165

Charge (pH=7)   0.873739834

Topological polar surface area  801.67

Aromaticity  0.043478261

Average rotatable bonds  3.347826087

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  34

X logP energy  -5.7365

Hydropathy 



Literature Information


Title  Purification and characterization of multiple components of human lymphoblastoid interferon-alpha.

DOI  NA,

Publication Year  1992

PubMed ID  1634550,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.