SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02386

Signal sequence   MALSFSLLMAVLVLSYKSICSLG

Length  23

Organism  Homo sapiens (Human)

UniProt ID  P01568,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02386.cif

Structure  SPKB02386.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2447.04744

Aliphatic index  152.6086957

Isoelectric point  8.522939048

Charge (pH=7)   0.934864135

Topological polar surface area  850.92

Aromaticity  0.086956522

Average rotatable bonds  3.52173913

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  34

X logP energy  -4.9127

Hydropathy 



Literature Information


Title  Purification and characterization of multiple components of human lymphoblastoid interferon-alpha.

DOI  NA,

Publication Year  1992

PubMed ID  1634550,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.