SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02385

Signal sequence   MARSFSLLMVVLVLSYKSICSLG

Length  23

Organism  Homo sapiens (Human)

UniProt ID  P01567,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02385.cif

Structure  SPKB02385.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2518.12934

Aliphatic index  143.9130435

Isoelectric point  9.447869836

Charge (pH=7)   1.934860824

Topological polar surface area  912.82

Aromaticity  0.086956522

Average rotatable bonds  3.652173913

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  35

X logP energy  -6.05943

Hydropathy 



Literature Information


Title  Identification of nine interferon-alpha subtypes produced by Sendai virus-induced human peripheral blood leucocytes.

DOI  10.1042/bj3290295,

Publication Year  1998

PubMed ID  9425112,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.