SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02383

Signal sequence   MASPFALLMVLVVLSCKSSCSLG

Length  23

Organism  Homo sapiens (Human)

UniProt ID  P01562,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02383.cif

Structure  SPKB02383.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2356.94074

Aliphatic index  131.3043478

Isoelectric point  8.229691165

Charge (pH=7)   0.873739834

Topological polar surface area  821.9

Aromaticity  0.043478261

Average rotatable bonds  3.304347826

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  34

X logP energy  -6.8612

Hydropathy 



Literature Information


Title  Purification and characterization of multiple components of human lymphoblastoid interferon-alpha.

DOI  NA,

Publication Year  1992

PubMed ID  1634550,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.