SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02381

Signal sequence   MVKIIFVFFIFLSSFSYA

Length  18

Organism  Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

UniProt ID  P01555,

Motif  1..18



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02381.cif

Structure  SPKB02381.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2159.65714

Aliphatic index  124.4444444

Isoelectric point  9.298300651

Charge (pH=7)   0.996838851

Topological polar surface area  664.96

Aromaticity  0.333333333

Average rotatable bonds  3.722222222

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  25

X logP energy  1.177

Hydropathy 



Literature Information


Title  Isolation and characterization of a precursor form of the 'A' subunit of cholera toxin.

DOI  10.1016/0014-5793(81)80238-4,

Publication Year  1981

PubMed ID  7238869,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.