SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02380

Signal sequence   MISMLRCIYLFLSVILITSYFVTPVMP

Length  27

Organism  Apis mellifera (Honeybee)

UniProt ID  P01500,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02380.cif

Structure  SPKB02380.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3151.97574

Aliphatic index  147.7777778

Isoelectric point  8.506546087

Charge (pH=7)   0.934305444

Topological polar surface area  1005.85

Aromaticity  0.148148148

Average rotatable bonds  3.592592593

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  40

X logP energy  -1.07483

Hydropathy 



Literature Information


Title  Sequence analysis of bee venom neurotoxin (apamine) from its tryptic and chymotryptic cleavage products

DOI  NA,

Publication Year  1967

PubMed ID  5601655,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.