SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02377

Signal sequence   MNYLVMISLALLFVTGVES

Length  19

Organism  Androctonus australis (Sahara scorpion)

UniProt ID  P01484,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02377.cif

Structure  SPKB02377.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2100.55934

Aliphatic index  153.6842105

Isoelectric point  3.849982713

Charge (pH=7)   -1.001090992

Topological polar surface area  748.43

Aromaticity  0.105263158

Average rotatable bonds  3.578947368

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  28

X logP energy  -3.2227

Hydropathy 



Literature Information


Title  The amino-acid sequence of neurotoxin II of Androctonus australis Hector.

DOI  10.1111/j.1432-1033.1972.tb01924.x,

Publication Year  1972

PubMed ID  4342910,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.