SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02373

Signal sequence   MSSRLLLQLLGFWLFLSQPCRA

Length  22

Organism  Rattus norvegicus (Rat)

UniProt ID  P01347,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02373.cif

Structure  SPKB02373.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2580.14724

Aliphatic index  128.6363636

Isoelectric point  10.52640717

Charge (pH=7)   1.936002961

Topological polar surface area  952.09

Aromaticity  0.136363636

Average rotatable bonds  3.772727273

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  32

X logP energy  -5.01396

Hydropathy 



Literature Information


Title  Limited sequence homology between porcine and rat relaxins: implications for physiological studies.

DOI  10.1210/endo-108-2-726,

Publication Year  1981

PubMed ID  7004862,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.