General Information
SPKB ID SPKB02372
Signal sequence MGIPVGKSMLVLLISLAFALCCIA
Length 24
Organism Rattus norvegicus (Rat)
UniProt ID P01346,
Motif 1..24
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02372.cif
Physicochemical Information
Molecular weight 2464.18244
Aliphatic index 166.6666667
Isoelectric point 8.229691165
Charge (pH=7) 0.873739834
Topological polar surface area 790.31
Aromaticity 0.041666667
Average rotatable bonds 3.333333333
Number of hydrogen bond donors 29
Number of hydrogen bond acceptors 32
X logP energy -2.2197
Hydropathy 
Literature Information
Title Purification and primary structure of a polypeptide with multiplication-stimulating activity from rat liver cell cultures. Homology with human insulin-like growth factor II.
DOI NA,
Publication Year 1981
PubMed ID 7016879,
Patent ID NA,
