General Information
SPKB ID SPKB02371
Signal sequence MGIPMGKSMLVLLTFLAFASCCIA
Length 24
Organism Homo sapiens (Human)
UniProt ID P01344,
Motif 1..24
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 8U4C,
Predicted Structure ID SPKB02371.cif
Physicochemical Information
Molecular weight 2518.20534
Aliphatic index 122.0833333
Isoelectric point 8.229691165
Charge (pH=7) 0.873739834
Topological polar surface area 810.54
Aromaticity 0.083333333
Average rotatable bonds 3.375
Number of hydrogen bond donors 30
Number of hydrogen bond acceptors 34
X logP energy -3.5913
Hydropathy 
Literature Information
Title Primary structure of human insulin-like growth factor II.
DOI 10.1016/0014-5793(78)80237-3,
Publication Year 1978
PubMed ID 658418,
Patent ID NA,
