SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02369

Signal sequence   MALWMRFLPLLALLFLWESHPTQA

Length  24

Organism  Mus musculus (Mouse)

UniProt ID  P01326,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02369.cif

Structure  SPKB02369.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2885.52374

Aliphatic index  126.25

Isoelectric point  7.551312718

Charge (pH=7)   0.090665202

Topological polar surface area  958.05

Aromaticity  0.166666667

Average rotatable bonds  3.625

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  33

X logP energy  0.11557

Hydropathy 



Literature Information


Title  Amino acid sequence of the two insulins from mouse (Maus musculus).

DOI  10.1515/bchm2.1972.353.1.451,

Publication Year  1972

PubMed ID  5063718,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.