SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02368

Signal sequence   MALLVHFLPLLALLALWEPKPTQA

Length  24

Organism  Mus musculus (Mouse)

UniProt ID  P01325,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02368.cif

Structure  SPKB02368.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2686.33724

Aliphatic index  158.75

Isoelectric point  7.549726882

Charge (pH=7)   0.090373479

Topological polar surface area  877.36

Aromaticity  0.083333333

Average rotatable bonds  3.375

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  31

X logP energy  0.4974

Hydropathy 



Literature Information


Title  Amino acid sequence of the two insulins from mouse (Maus musculus).

DOI  10.1515/bchm2.1972.353.1.451,

Publication Year  1972

PubMed ID  5063718,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.