General Information
SPKB ID SPKB02366
Signal sequence MALWMRFLPLLALLVLWEPKPAQA
Length 24
Organism Rattus norvegicus (Rat)
UniProt ID P01322,
Motif 1..24
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02366.cif
Physicochemical Information
Molecular weight 2808.52494
Aliphatic index 142.5
Isoelectric point 9.695027686
Charge (pH=7) 0.999461077
Topological polar surface area 906.14
Aromaticity 0.125
Average rotatable bonds 3.541666667
Number of hydrogen bond donors 30
Number of hydrogen bond acceptors 31
X logP energy 1.84507
Hydropathy
Literature Information
Title Proinsulin and the biosynthesis of insulin.
DOI 10.1016/b978-0-12-571125-8.50008-9,
Publication Year 1969
PubMed ID 4311938,
Patent ID NA,