General Information
SPKB ID SPKB02364
Signal sequence MALWTRLRPLLALLALWPPPPARA
Length 24
Organism Bos taurus (Bovine)
UniProt ID P01317,
Motif 1..24
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 6ZI8,
Predicted Structure ID SPKB02364.cif
Physicochemical Information
Molecular weight 2724.39514
Aliphatic index 134.5833333
Isoelectric point 12.801071
Charge (pH=7) 2.997974365
Topological polar surface area 926.18
Aromaticity 0.083333333
Average rotatable bonds 3.166666667
Number of hydrogen bond donors 32
Number of hydrogen bond acceptors 30
X logP energy -1.12639
Hydropathy
Literature Information
Title The disulphide bonds of insulin.
DOI 10.1042/bj0600541,
Publication Year 1955
PubMed ID 13249947,
Patent ID NA,