SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02364

Signal sequence   MALWTRLRPLLALLALWPPPPARA

Length  24

Organism  Bos taurus (Bovine)

UniProt ID  P01317,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  6ZI8,

Predicted Structure ID  SPKB02364.cif

Structure  SPKB02364.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2724.39514

Aliphatic index  134.5833333

Isoelectric point  12.801071

Charge (pH=7)   2.997974365

Topological polar surface area  926.18

Aromaticity  0.083333333

Average rotatable bonds  3.166666667

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  30

X logP energy  -1.12639

Hydropathy 



Literature Information


Title  The disulphide bonds of insulin.

DOI  10.1042/bj0600541,

Publication Year  1955

PubMed ID  13249947,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.