SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02363

Signal sequence   MALWTRLLPLLALLALWAPAPAQA

Length  24

Organism  Sus scrofa (Pig)

UniProt ID  P01315,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02363.cif

Structure  SPKB02363.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2601.23444

Aliphatic index  159.1666667

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  863.05

Aromaticity  0.083333333

Average rotatable bonds  3.125

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  29

X logP energy  -0.31393

Hydropathy 



Literature Information


Title  Porcine proinsulin: characterization and amino acid sequence.

DOI  10.1126/science.161.3837.165,

Publication Year  1968

PubMed ID  5657063,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.