General Information
SPKB ID SPKB02362
Signal sequence MALWMRLLPLLALLALWGPDPAAA
Length 24
Organism Homo sapiens (Human)
UniProt ID P01308,
Motif 1..24
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 6B3Q,
Predicted Structure ID SPKB02362.cif
Physicochemical Information
Molecular weight 2604.25294
Aliphatic index 155
Isoelectric point 6.338718596
Charge (pH=7) -0.001572528
Topological polar surface area 837.03
Aromaticity 0.083333333
Average rotatable bonds 3.166666667
Number of hydrogen bond donors 28
Number of hydrogen bond acceptors 29
X logP energy 0.87907
Hydropathy
Literature Information
Title Amino-acid sequence of human insulin.
DOI 10.1038/187483a0,
Publication Year 1960
PubMed ID 14426955,
Patent ID NA,