SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02361

Signal sequence   MLGNKRLGLSGLTLALSLLVCLGALAEA

Length  28

Organism  Homo sapiens (Human)

UniProt ID  P01303,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02361.cif

Structure  SPKB02361.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2798.43844

Aliphatic index  163.9285714

Isoelectric point  8.545125282

Charge (pH=7)   0.937486361

Topological polar surface area  1078.02

Aromaticity  0

Average rotatable bonds  3.428571429

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  38

X logP energy  -8.60913

Hydropathy 



Literature Information


Title  Cloning, characterization, and DNA sequence of a human cDNA encoding neuropeptide tyrosine.

DOI  10.1073/pnas.81.14.4577,

Publication Year  1984

PubMed ID  6589611,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.