SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02357

Signal sequence   MMSAKDTVKVMVVMLAICFLARSDG

Length  25

Organism  Sus scrofa (Pig)

UniProt ID  P01269,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02357.cif

Structure  SPKB02357.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2717.37234

Aliphatic index  105.2

Isoelectric point  8.5404189

Charge (pH=7)   0.936309173

Topological polar surface area  1010.95

Aromaticity  0.04

Average rotatable bonds  3.72

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  39

X logP energy  -7.49213

Hydropathy 



Literature Information


Title  Porcine proparathyroid hormone. Identification, biosynthesis, and partial amino acid sequence.

DOI  10.1021/bi00687a018,

Publication Year  1975

PubMed ID  1164500,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.