SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02356

Signal sequence   MMSAKDMVKVMIVMLAICFLARSDG

Length  25

Organism  Bos taurus (Bovine)

UniProt ID  P01268,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02356.cif

Structure  SPKB02356.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2761.48664

Aliphatic index  109.2

Isoelectric point  8.5404189

Charge (pH=7)   0.936309173

Topological polar surface area  990.72

Aromaticity  0.04

Average rotatable bonds  3.84

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  39

X logP energy  -5.72973

Hydropathy 



Literature Information


Title  The N-terminal amino-acid sequence of bovine proparathyroid hormone.

DOI  10.1073/pnas.71.3.653,

Publication Year  1974

PubMed ID  4522780,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.