SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02354

Signal sequence   MAAGSRTSLLLAFGLLCLSWLQEGSA

Length  26

Organism  Homo sapiens (Human)

UniProt ID  P01242,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02354.cif

Structure  SPKB02354.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2696.17474

Aliphatic index  120.3846154

Isoelectric point  6.232433001

Charge (pH=7)   -0.062218605

Topological polar surface area  1050.05

Aromaticity  0.076923077

Average rotatable bonds  3.384615385

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  37

X logP energy  -9.79203

Hydropathy 



Literature Information


Title  Identification of placental human growth hormone as the growth hormone-V gene expression product.

DOI  10.1210/jcem-71-1-15,

Publication Year  1990

PubMed ID  2196278,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.