SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02353

Signal sequence   MATGSRTSLLLAFGLLCLPWLQEGSA

Length  26

Organism  Homo sapiens (Human)

UniProt ID  P01241,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02353.cif

Structure  SPKB02353.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2736.23954

Aliphatic index  116.5384615

Isoelectric point  6.232433001

Charge (pH=7)   -0.062218605

Topological polar surface area  1041.26

Aromaticity  0.076923077

Average rotatable bonds  3.346153846

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  37

X logP energy  -8.91723

Hydropathy 



Literature Information


Title  Human pituitary growth hormone. 32. The primary structure of the hormone: revision.

DOI  10.1016/s0003-9861(71)80060-7,

Publication Year  1971

PubMed ID  5144027,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.