SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02351

Signal sequence   MDSKGSSQKGSRLLLLLVVSNLLLCQGVVS

Length  30

Organism  Bos taurus (Bovine)

UniProt ID  P01239,

Motif  1..30



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  5B4W,

Predicted Structure ID  SPKB02351.cif

Structure  SPKB02351.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3145.76664

Aliphatic index  142.6666667

Isoelectric point  9.673752869

Charge (pH=7)   1.935862689

Topological polar surface area  1309.11

Aromaticity  0

Average rotatable bonds  3.7

Number of hydrogen bond donors  47

Number of hydrogen bond acceptors  46

X logP energy  -14.61643

Hydropathy 



Literature Information


Title  An evidence for deamidation of prolactin monomer.

DOI  NA,

Publication Year  1970

PubMed ID  5507606,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.