SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02349

Signal sequence   MNSQVSARKAGTLLLLMMSNLLFCQNVQT

Length  29

Organism  Rattus norvegicus (Rat)

UniProt ID  P01237,

Motif  1..29



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02349.cif

Structure  SPKB02349.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3212.84944

Aliphatic index  107.5862069

Isoelectric point  9.833242293

Charge (pH=7)   1.935711238

Topological polar surface area  1325.73

Aromaticity  0.034482759

Average rotatable bonds  3.827586207

Number of hydrogen bond donors  46

Number of hydrogen bond acceptors  47

X logP energy  -14.78223

Hydropathy 



Literature Information


Title  Complete amino acid sequence of the precursor region of rat prolactin.

DOI  10.1021/bi00617a022,

Publication Year  1978

PubMed ID  728396,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.