SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02346

Signal sequence   MEMLQGLLLWLLLGVAGVWA

Length  20

Organism  Ovis aries (Sheep)

UniProt ID  P01231,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02346.cif

Structure  SPKB02346.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2213.76734

Aliphatic index  175.5

Isoelectric point  3.849983241

Charge (pH=7)   -1.000240578

Topological polar surface area  728.19

Aromaticity  0.1

Average rotatable bonds  3.55

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  25

X logP energy  1.2627

Hydropathy 



Literature Information


Title  Renotropic activity in ovine luteinizing hormone isoform(s).

DOI  10.1210/endo-123-2-700,

Publication Year  1988

PubMed ID  2456202,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.