SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02344

Signal sequence   MKTLQFFFLFCCWKAICC

Length  18

Organism  Homo sapiens (Human)

UniProt ID  P01225,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02344.cif

Structure  SPKB02344.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2232.82364

Aliphatic index  70.55555556

Isoelectric point  8.3409973

Charge (pH=7)   1.749495368

Topological polar surface area  689.17

Aromaticity  0.277777778

Average rotatable bonds  3.888888889

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  28

X logP energy  -0.1305

Hydropathy 



Literature Information


Title  A reevaluation of the amino acid sequence of human follitropin beta-subunit.

DOI  10.1007/BF01024882,

Publication Year  1988

PubMed ID  3151250,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.