SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02343

Signal sequence   MTATFLMSMIFGLACGQAMS

Length  20

Organism  Bos taurus (Bovine)

UniProt ID  P01223,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02343.cif

Structure  SPKB02343.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2111.59334

Aliphatic index  73.5

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  740.23

Aromaticity  0.1

Average rotatable bonds  3.45

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  31

X logP energy  -6.4904

Hydropathy 



Literature Information


Title  The primary structure of bovine thyrotropin. II. The amino acid sequences of the reduced, S-carboxymethyl alpha and beta chains.

DOI  NA,

Publication Year  1971

PubMed ID  5101174,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.