General Information
SPKB ID SPKB02342
Signal sequence MTALFLMSMLFGLTCGQAMS
Length 20
Organism Homo sapiens (Human)
UniProt ID P01222,
Motif 1..20
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02342.cif
Physicochemical Information
Molecular weight 2153.67394
Aliphatic index 88
Isoelectric point 5.922539791
Charge (pH=7) -0.063990417
Topological polar surface area 740.23
Aromaticity 0.1
Average rotatable bonds 3.55
Number of hydrogen bond donors 27
Number of hydrogen bond acceptors 31
X logP energy -5.4642
Hydropathy 
Literature Information
Title Human pituitary thyrotropin. The primary structure of the alpha and beta subunits.
DOI 10.1139/o77-108,
Publication Year 1977
PubMed ID 890569,
Patent ID NA,
