SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02340

Signal sequence   MDYYRKYAAIFLVTLSVFLHVLHS

Length  24

Organism  Homo sapiens (Human)

UniProt ID  P01215,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  7FIG,

Predicted Structure ID  SPKB02340.cif

Structure  SPKB02340.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2887.43534

Aliphatic index  125.8333333

Isoelectric point  9.05412368

Charge (pH=7)   1.177399378

Topological polar surface area  1036.58

Aromaticity  0.208333333

Average rotatable bonds  3.75

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  37

X logP energy  -2.96563

Hydropathy 



Literature Information


Title  The amino acid sequence of human chorionic gonadotropin. The alpha subunit and beta subunit.

DOI  NA,

Publication Year  1975

PubMed ID  1150658,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.