General Information
SPKB ID SPKB02335
Signal sequence MACPSLACCLLGLLALTSA
Length 19
Organism Rattus norvegicus (Rat)
UniProt ID P01179,
Motif 1..19
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB02335.cif
Physicochemical Information
Molecular weight 1851.32594
Aliphatic index 144.2105263
Isoelectric point 5.759310256
Charge (pH=7) -0.187939848
Topological polar surface area 639.02
Aromaticity 0
Average rotatable bonds 3
Number of hydrogen bond donors 25
Number of hydrogen bond acceptors 27
X logP energy -5.4736
Hydropathy
Literature Information
Title Evolution of neurohypophyseal hormones: isolation of active principles from rabbits and rats
DOI 10.1016/s0300-9084(71)80199-2,
Publication Year 1971
PubMed ID 5150741,
Patent ID NA,