SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02334

Signal sequence   MAGPSLACCLLGLLALTSA

Length  19

Organism  Homo sapiens (Human)

UniProt ID  P01178,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02334.cif

Structure  SPKB02334.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1805.23904

Aliphatic index  144.2105263

Isoelectric point  5.826007312

Charge (pH=7)   -0.125965132

Topological polar surface area  639.02

Aromaticity  0

Average rotatable bonds  2.947368421

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  26

X logP energy  -5.772

Hydropathy 



Literature Information


Title  On the nature of oxytocin and vasopressin from human pituitary.

DOI  10.3181/00379727-98-24154,

Publication Year  1958

PubMed ID  13591312,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.