SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02332

Signal sequence   MLSCRLQCALAALSIVLALGGVTG

Length  24

Organism  Sus scrofa (Pig)

UniProt ID  P01168,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02332.cif

Structure  SPKB02332.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2360.91704

Aliphatic index  154.5833333

Isoelectric point  8.231408964

Charge (pH=7)   0.874031556

Topological polar surface area  898.3

Aromaticity  0

Average rotatable bonds  3.25

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  33

X logP energy  -8.33593

Hydropathy 



Literature Information


Title  Prosomatostatin 1-64 is a major product of somatostatin gene expression in pancreas and gut.

DOI  NA,

Publication Year  1989

PubMed ID  2567292,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.