SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02331

Signal sequence   MVSTMLSGLVLWLTFGWTPALA

Length  22

Organism  Sus scrofa (Pig)

UniProt ID  P01165,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02331.cif

Structure  SPKB02331.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2394.91544

Aliphatic index  124.0909091

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  798.36

Aromaticity  0.136363636

Average rotatable bonds  3.227272727

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  30

X logP energy  -2.7457

Hydropathy 



Literature Information


Title  Processed forms of neuroendocrine proteins 7B2 and secretogranin II are found in porcine pituitary extracts.

DOI  10.1111/j.1399-3011.1991.tb01519.x,

Publication Year  1991

PubMed ID  1797712,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.