SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB02330

Signal sequence   MGSFSITKGFFLFLAFWLPGHIGA

Length  24

Organism  Rattus norvegicus (Rat)

UniProt ID  P01161,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB02330.cif

Structure  SPKB02330.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2645.15964

Aliphatic index  89.58333333

Isoelectric point  9.702001779

Charge (pH=7)   1.088598356

Topological polar surface area  855.01

Aromaticity  0.25

Average rotatable bonds  3.333333333

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  31

X logP energy  -1.9984

Hydropathy 



Literature Information


Title  NH2-terminal fragment of rat pro-atrial natriuretic factor in the circulation: identification, radioimmunoassay and half-life.

DOI  10.1016/0196-9781(88)90008-3,

Publication Year  1988

PubMed ID  2966345,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.